Brain Inflammation

Brain Inflammation
Brain Inflammation
Brain inflammation, known as encephalitis, occurs due to infections, autoimmune disorders, and various other factors that provoke an immune response within the brain. Chronic systemic inflammation: Conditions like gut inflammation, autoimmune disorders (for instance, rheumatoid arthritis), and obesity can lead to ongoing inflammation across the body, potentially impacting the brain through a compromised blood-brain barrier. This prolonged inflammation serves as a risk factor and a precursor for various severe chronic illnesses, such as type 2 diabetes, cardiovascular diseases, cancer, and autoimmune conditions.

Possible risk factors could include infections, poor diet, lack of physical activity, environmental toxins, strokes, elevated blood sugar, high blood pressure, high cholesterol, traumatic brain injuries, tumors, the Covid-19 mRNA vaccine, heavy metals, chronic constipation, senescent cells, microplastics, and persistent psychological stress.

High cholesterol can lead to brain inflammation via various mechanisms, such as compromising the blood-brain barrier (BBB), directly triggering inflammation and oxidative stress in brain cells, aiding in the development of amyloid plaques linked to Alzheimer's disease, and exacerbating cerebrovascular issues. This inflammation can harm brain tissues, disrupt neuronal communication, and impact cognitive abilities like memory and attention.

According to Traditional Chinese Medicine (TCM), foods that are considered "heaty," particularly those that are cooked at elevated temperatures or are high in fat, trans fats, refined carbohydrates, and sugar, may lead to inflammation. Cooking techniques such as deep frying and grilling can generate substances known as Advanced Glycation End-products (AGEs), which can encourage inflammatory processes within the body.

Symptoms of Brain Inflammation: Chronic headaches, migraine, fever, neck stiffness, fatigue, sleep disorder,  scalp pain, and tinnitus or ringing in the ears.

Brain inflammation is a serious medical condition. If you have a severe headache, fever, or notice any changes in your consciousness, please seek medical attention right away.

 Nutritional Supplements Aimed at Alleviating Inflammation:


Common supplements that are often utilized to alleviate brain inflammation consist of omega-3 fatty acids, curcumin (derived from turmeric), vitamin D, ginger, probiotics, resveratrol, and green tea extract. These supplements function by addressing inflammatory pathways, offering antioxidant benefits, enhancing the gut-brain connection, and safeguarding brain cells.

Supplements that could assist in lowering TNF-α and IL-6 levels are curcumin, omega-3 fatty acids, coenzyme Q10, propolis, aged garlic extract, and Ginkgo biloba.

Additionally, vitamin B6, ginger, and vitamin D3 are other alternatives that have demonstrated possible advantages in decreasing these inflammatory markers.

Supplements are not capable of curing severe medical conditions such as brain inflammation; however, specific nutrients have shown anti-inflammatory and neuroprotective effects that could assist in managing symptoms and promoting brain health.


Brain inflammation, referred to as neuroinflammation, may arise from infections, injuries, or autoimmune disorders and necessitates immediate medical attention. It is important to note that supplements are regarded as a complementary approach rather than a primary form of treatment.

Green Tea Extract
:

Green tea extract has the potential to diminish brain inflammation by utilizing its active compounds, especially catechins such as EGCG, which are known for their potent antioxidant and anti-inflammatory characteristics. These elements work against oxidative stress,
prevent cytokine production, and may also inhibit microglial activation, a significant contributor to neuroinflammation in various neurological disorders.

Recommended Products:
Biocare Green Tea Extract

NOW Foods EGCg Green Tea Extract 400mg
Organixs Premium Green Tea Extract
Horbäach Green Tea Extract Capsules 450mg
SWISSE Ultiboost *Milk Thistle + Green Tea Complex
*The active compound of milk thistle, silymarin, has antioxidant and anti-inflammatory characteristics that could potentially aid in diminishing brain inflammation.

Sacha Inchi Oil + Vitamin D

Sacha inchi oil demonstrates potential in alleviating brain inflammation.

This is attributed to its rich composition of omega-3 and omega-6 fatty acids, along with antioxidants. These elements exhibit anti-inflammatory characteristics and have been associated with neuroprotective benefits in numerous studies, which could assist in reducing inflammation in the brain.

Vitamin D has the ability to diminish brain inflammation due to its anti-inflammatory characteristics and its impact on several cellular pathways within the brain, which includes the functioning of immune cells. Additionally, it aids in preserving the integrity of the brain's protective barriers and encourages the production of neuroprotective compounds such as BDNF, which are advantageous for brain health. Research indicates that vitamin D supplementation can alleviate injury and inflammation, especially following occurrences such as ischemic stroke and traumatic brain injury.

Product:
Infinity Sacha Inchi Oil 1000 mg with Vitamin D3 1000 IU
Bonlife Sacha Inchi Q10 Plus
D'Medy 60 Softgel Minyak Sacha Inchi Oil + Sea Buckthorn Oil & Vitamin D3
bplife Sacha Inchi Oil Vitamin E
MYRITA SACHA INCHI OIL PLUS SEABUCKTHORN SEED OIL ASTAXANTHIN & D3 SOFTGEL 60S
Curcumin

Curcumin demonstrates potential in alleviating brain inflammation owing to its strong antioxidant and anti-inflammatory characteristics, which aid in inhibiting inflammatory mediators, decreasing oxidative stress, and regulating essential inflammatory signaling pathways such as NF-κB and the MAPK pathway.

Research indicates that curcumin is capable of traversing the blood-brain barrier, engaging with inflammatory molecules, and may provide protective advantages against neurodegenerative disorders like Alzheimer's.

𝗖𝗨𝗥𝗖𝗨𝗠𝗜𝗡 𝗵𝗮𝘀 𝗯𝗲𝗲𝗻 𝗹𝗶𝗻𝗸𝗲𝗱 𝘁𝗼 𝗶𝗺𝗽𝗿𝗼𝘃𝗲𝗱 𝗷𝗼𝗶𝗻𝘁 𝗵𝗲𝗮𝗹𝘁𝗵, 𝗯𝗲𝘁𝘁𝗲𝗿 𝗯𝗿𝗮𝗶𝗻 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻, 𝗲𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗱𝗶𝗴𝗲𝘀𝘁𝗶𝗼𝗻, 𝗮𝗻𝗱 𝘀𝘁𝗿𝗼𝗻𝗴𝗲𝗿 𝗶𝗺𝗺𝘂𝗻𝗶𝘁𝘆. 𝗔𝗱𝗱𝗶𝘁𝗶𝗼𝗻𝗮𝗹𝗹𝘆, 𝗶𝘁 𝘀𝗵𝗼𝘄𝘀 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗶𝗻 𝗺𝗮𝗻𝗮𝗴𝗶𝗻𝗴 𝗰𝗵𝗿𝗼𝗻𝗶𝗰 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 𝗹𝗶𝗸𝗲 𝗵𝗲𝗮𝗿𝘁 𝗱𝗶𝘀𝗲𝗮𝘀𝗲, 𝗮𝗿𝘁𝗵𝗿𝗶𝘁𝗶𝘀 𝗮𝗻𝗱 𝗱𝗶𝗮𝗯𝗲𝘁𝗲𝘀 𝘄𝗵𝗶𝗹𝗲 𝗽𝗿𝗼𝗺𝗼𝘁𝗶𝗻𝗴 𝗴𝗹𝗼𝘄𝗶𝗻𝗴 𝘀𝗸𝗶𝗻 𝗮𝗻𝗱 𝗼𝘃𝗲𝗿𝗮𝗹𝗹 𝘃𝗶𝘁𝗮𝗹𝗶𝘁𝘆.

𝗖𝗨𝗥𝗖𝗨𝗠𝗜𝗡 𝗲𝘅𝘁𝗿𝗮𝗰𝘁 𝗶𝘀 𝗺𝗼𝗿𝗲 𝗲𝗳𝗳𝗲𝗰𝘁𝗶𝘃𝗲 𝘁𝗵𝗮𝗻 𝗿𝗮𝘄 𝘁𝘂𝗿𝗺𝗲𝗿𝗶𝗰 𝗮𝘀 𝗶𝘁 𝗱𝗲𝗹𝗶𝘃𝗲𝗿𝘀 𝗮 𝗰𝗼𝗻𝗰𝗲𝗻𝘁𝗿𝗮𝘁𝗲𝗱 𝗱𝗼𝘀𝗲 𝗼𝗳 𝗰𝘂𝗿𝗰𝘂𝗺𝗶𝗻, 𝗼𝘃𝗲𝗿𝗰𝗼𝗺𝗶𝗻𝗴 𝘁𝘂𝗿𝗺𝗲𝗿𝗶𝗰’𝘀 𝗹𝗼𝘄 𝗰𝘂𝗿𝗰𝘂𝗺𝗶𝗻 𝗰𝗼𝗻𝘁𝗲𝗻𝘁 𝗮𝗻𝗱 𝗽𝗼𝗼𝗿 𝗮𝗯𝘀𝗼𝗿𝗽𝘁𝗶𝗼𝗻. 𝗢𝗳𝘁𝗲𝗻 𝗰𝗼𝗺𝗯𝗶𝗻𝗲𝗱 𝘄𝗶𝘁𝗵 𝗣𝗜𝗣𝗘𝗥𝗜𝗡𝗘 (𝗯𝗹𝗮𝗰𝗸 𝗽𝗲𝗽𝗽𝗲𝗿 𝗲𝘅𝘁𝗿𝗮𝗰𝘁) 𝗳𝗼𝗿 𝗲𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗯𝗶𝗼𝗮𝘃𝗮𝗶𝗹𝗮𝗯𝗶𝗹𝗶𝘁𝘆, 𝗰𝘂𝗿𝗰𝘂𝗺𝗶𝗻 𝗲𝘅𝘁𝗿𝗮𝗰𝘁 𝗲𝗻𝘀𝘂𝗿𝗲𝘀 𝘁𝗵𝗲 𝗯𝗼𝗱𝘆 𝗰𝗮𝗻 𝗳𝘂𝗹𝗹𝘆 𝗯𝗲𝗻𝗲𝗳𝗶𝘁 𝗳𝗿𝗼𝗺 𝗶𝘁𝘀 𝗮𝗻𝘁𝗶-𝗶𝗻𝗳𝗹𝗮𝗺𝗺𝗮𝘁𝗼𝗿𝘆 𝗮𝗻𝗱 𝗮𝗻𝘁𝗶𝗼𝘅𝗶𝗱𝗮𝗻𝘁 𝗽𝗿𝗼𝗽𝗲𝗿𝘁𝗶𝗲𝘀.

Lecithin and bioflavonoids are sometimes combined with curcumin to improve its absorption and therapeutic effects.

Products:
Kordel's Bio-Curmin
Kordel's Bio-Curmin Turmeric 100mg with Theracurmin for Brain, Cancer, Joint, Bone, Cartilage.
For health protection, take 1 capsule of 100 mg of Theracurmin® twice a day.
For therapeutic / treatment purposes, take up to 3 capsules of 100mg Theracurmin® twice a day.

now CurcuBrain
Life Extension] Curcumin Elite™ Turmeric Extract
Bio-life Herbalmeds Curcure Phyto

LIVEWELL CURQMIN
PipingRock Turmeric Curcumin
Naturewells Turmeric Curcumin Extract
𝗨𝗧𝗠 𝗡𝗨𝗧𝗥𝗘𝗟𝗟 𝗧𝗨𝗥𝗠𝗘𝗥𝗜𝗖 𝗣𝗟𝗨𝗦
Carlyle Turmeric Curcumin with Bioperine
Horbaach Turmeric Curcumin with Black Pepper

VitaHealth Supa Garlic Plus
Each softgel contains:
Garlic oil......................................1mg
Lecithin...................................1100mg
Wheatgerm oil..........................100mg

Lecithin may possess anti-inflammatory properties that could aid in diminishing brain inflammation. Additionally, lecithin may assist in safeguarding brain cells against oxidative stress, a mechanism that can lead to inflammation and neuronal injury.

Compounds found in garlic, including SAC and various sulfur-containing molecules, have the potential to reduce neuroinflammatory responses and microglial activation within the brain.

Research indicates that wheatgerm oil (WGO) possesses anti-inflammatory and neuroprotective characteristics, which could potentially aid in diminishing brain inflammation.


Curcumin + Other Compounds

There are numerous compounds and advanced delivery systems that can be combined with curcumin to significantly boost its bioavailability.

Due to its low solubility in water, rapid metabolism, and elimination, curcumin by itself is not easily absorbed by the body.

The active ingredient in black pepper is among the most effective and commonly used enhancers of curcumin's bioavailability.

As curcumin is fat-soluble, pairing it with healthy fats, such as those found in fish oil, can greatly enhance its absorption. The omega-3 fatty acids present in fish oil assist in dissolving curcumin, allowing for better absorption by the digestive system.

Phospholipids (lecithin): Certain supplements form a "phytosome" by attaching curcumin to a phospholipid like lecithin. This fat-soluble complex is highly absorbable and has been demonstrated in studies to significantly improve bioavailability compared to standard curcumin.
These two powerful antioxidants have been shown to have a synergistic effect on curcumin absorption when used together.

Quercetin and resveratrol: These two powerful antioxidants have demonstrated a synergistic effect on the absorption of curcumin when used together.


Lecithin + Curcumin
The combination of curcumin with lecithin enhances its potency by greatly improving its bioavailability, thereby enabling the body to absorb it more efficiently. This enhancement occurs because lecithin creates complexes with curcumin, referred to as phytosomes, which increases its solubility and facilitates its passage across the intestinal barrier, resulting in elevated levels of curcumin in the bloodstream.
 
Lecithin + Vitamin A & D
The combination of lecithin with vitamins A and D has been shown to lower inflammatory markers and oxidative stress, thereby enhancing cognitive function.
This process operates by modulating neurotrophic factors and reducing microglial activation, which is a crucial element in brain inflammation.

Product:
Powerlife K2D3
Now Foods Vitamin A, 10,000 IU
Note: It's beneficial to take vitamin D with vitamin k2 , and Magnesium.
 
Curcumin + Olive Leaf Extract
The combination of curcumin and olive leaf extract can result in stronger effects.
Both of these compounds possess antioxidant and anti-inflammatory qualities, and when used together, they seem to provide synergistic advantages for immune support and inflammation reduction. Research indicates that they may boost each other's effectiveness for specific health conditions.

Product:
Carlyle Olive Leaf Extract
NOW Foods Olive Leaf Extract

Curcumin + Lecithin + Olive Leaf Extract

Curcumin can be paired with olive leaf extract and lecithin, which is recognized for boosting curcumin's effectiveness and bioavailability. Lecithin creates phytosome complexes with curcumin, enhancing its solubility and shielding it from degradation, thus allowing more of it to be absorbed and utilized by the body. Research indicates that this curcumin-lecithin complex can be beneficial for a range of health issues, including joint health. Merging it with olive leaf extract is a practical strategy, as both compounds are antioxidants and possess anti-inflammatory characteristics.

Curcumin + Grape Seed Extract
Combining curcumin with grape seed extract can create a stronger impact, especially regarding their anti-inflammatory and antioxidant properties.
This illustrates a synergistic effect, where the overall result is more significant than the mere addition of each component.

Curcumin + Tart Cherry Extract + Piperine
Curcumin: This active ingredient found in turmeric serves as a powerful antioxidant and anti-inflammatory substance. Research indicates that it may be able to cross the blood-brain barrier, lowering neuroinflammation markers and potentially aiding in age-related cognitive decline and neurodegenerative disorders. The piperine compound present in black pepper greatly enhances the bioavailability and absorption of curcumin in the body, as curcumin is typically absorbed poorly.

Tart cherry extract: Packed with anti-inflammatory and antioxidant polyphenols, including anthocyanins, tart cherries have demonstrated the ability to decrease chronic inflammation and oxidative stress. Research has shown that tart cherry supplementation can lower inflammatory markers in the brain and enhance working memory. The synergistic antioxidant effects of tart cherry and turmeric create a powerful duo for overall health, particularly benefiting joint and heart wellness.

Curcumin + Black Seed Oil or Extract
Combining curcumin (derived from turmeric) with black seed oil (also known as black cumin oil) can result in a stronger effect, as the active compounds curcumin and thymoquinone work together synergistically. Research indicates that this combination may boost overall antioxidant levels, support healthy inflammatory and immune responses, and provide greater benefits for issues such as metabolic syndrome.

MINSYAM MINYAK HABBATUS SAUDA (BLACK SEED OIL)
Infinity Black Seed Oil Plus Olive Leaves Extract
Life Extension, Black Cumin Seed Oi (Nigella sativa)
Black seed oil contains thymoquinone and anthocyanins, which are powerful compounds known to fight inflammation and oxidative stress in the brain.
Thymoquinone is a lipophilic molecule with a low molecular weight, allowing it to cross the blood-brain barrier and exert its beneficial effects directly in the brain.


Black seed oil and Omega-3 fish oil  both act as blood thinners by inhibiting blood clotting and possibly lowering platelet levels, which may elevate the risk of bleeding and bruising. Given these effects, it is essential to refrain from using them if you have a bleeding disorder or are scheduled for surgery. They may interfere with the effects of anticoagulant medications like warfarin. This is an important consideration for anyone taking blood-thinning drugs.

Curcumin + Quercetin
Studies suggest that the combination of curcumin and quercetin could yield a more effective anti-inflammatory response than using either compound by itself. This synergistic effect is believed to arise from the fact that these two compounds operate through distinct yet complementary anti-inflammatory mechanisms, including the downregulation of pro-inflammatory markers such as COX-2 and TNF-α, the inhibition of the NF-κB pathway, and the reduction of oxidative stress.

Curcumin + Quercetin + Lecithin
Curcumin combined with quercetin and lecithin probably offers superior anti-inflammatory benefits since curcumin and quercetin act together synergistically, and lecithin boosts the bioavailability of curcumin, which is not easily absorbed. Lecithin creates phytosomes that improve the absorption and anti-inflammatory properties of curcumin, while quercetin amplifies both the anti-inflammatory and cytotoxic effects of curcumin, making this combination a potent strategy for alleviating inflammation.
 
Curcumin + Lecithin + Olive Leaf Extract
Curcumin combined with lecithin may serve as a more powerful anti-inflammatory agent compared to regular curcumin, as lecithin enhances the bioavailability of curcumin. When paired with olive leaf extract (OLE), known for its strong anti-inflammatory and antioxidant effects, this combination is expected to provide even greater anti-inflammatory advantages.

Curcumin + Ginkgo
The combination of curcumin and Ginkgo biloba extract (GBE) might help decrease brain inflammation, since GBE can improve the brain's uptake of curcumin. This synergy allows their joint antioxidant and anti-inflammatory benefits to have a more pronounced impact on reducing neuroinflammation in research studies. Preclinical models indicate that this pairing significantly reduces pro-inflammatory cytokines such as TNF-α and IL-1β, hinting at a possible synergistic effect on brain health. Ginkgo biloba extract (GBE) also has the ability to lessen brain inflammation thanks to its antioxidant and anti-inflammatory characteristics.
 
Curcumin + Black Garlic Extract
Curcumin and black garlic: Both serve as powerful antioxidants that may assist in alleviating oxidative stress, a mechanism that plays a role in inflammation across the body, including the brain.
Curcumin: It is capable of traversing the blood-brain barrier and has been demonstrated in animal research to stimulate protective pathways (such as Nrf2) while suppressing inflammatory pathways (such as NF-κB), which could lead to a decrease in neuroinflammation.

Curcumin + Cod Liver Oil
Cod liver oil and curcumin can synergistically reduce inflammation, as both substances are anti-inflammatory on their own and might enhance each other's absorption. Curcumin, the active ingredient in turmeric, functions by inhibiting pro-inflammatory pathways, whereas the omega-3 fatty acids found in cod liver oil assist in suppressing the proteins that encourage chronic inflammation. The combination of these two may provide a stronger anti-inflammatory effect for a range of conditions, including heart and metabolic health.

Curcumin + Black Seasame Seed Extract + Boswellia
The combination of curcumin and black sesame seed extract, especially when boswellia is included, has demonstrated promise for providing quick and effective relief from acute musculoskeletal pain, similar to acetaminophen in certain clinical studies.

Curcumin and black sesame seed extract decrease brain inflammation by collaborating to eliminate free radicals, suppress inflammatory markers, and safeguard brain cells.

Black sesame is rich in lignans and vitamin E, which help prevent the oxidation of nerve cell membranes. Meanwhile, curcumin obstructs inflammatory pathways and boosts cellular antioxidant defenses. A clinical study even discovered that a mix of turmeric (curcumin) and black sesame seed extract was effective in alleviating acute pain.

Product:
SEIKETSU--BLACSEMENURO VEGETABLE CAPSULE 黑芝麻精华素.

Black sesame seeds have been know as health care products in the old days. Not only that, the black sesame seeds can treat many kind of diseases, helps to prolong life according to Compendium of Materia Medica. Black sesame seeds contain vitamins B1, B2, B6, C, E and dietary fiber. It's mineral components are calcium, phosphorus, iron, magnesium, potassium, sodium, rare element of zinc and selenium trace, nicotinic acid etc. It also contains sesamin, arachidic acid, sesamol, oleic acid, palmitic acid, stearic acid, sterol, lecithin, vitamin A, B, D, E and many other nutrients.

*Vitamin E can promote cell division, delayed cell senescence

*Polyphenols (such as anthocyanin, lignans and vitamins B1, etc) can improve the immune system to fight disease

*Contains lips to improve joint pain, relieve chronic neuritis, improve vision and dry itchy skin problems

*Smoothen the intestine to releases of constipation

*Vitamin E will invigorate the circulation of blood, achieve beauty and face care, moisture the skin linoleic acid, sesame oil and etc will prevent degradation of brain cells, strengthen brain and improve memory ability.

Megaflex™ Curcumin Extract and Boswellia Extract
Swanson Boswellia Double Strength
Carlyle Boswellia Extract Capsules
Oliferin Joint Flex Triva Curcumin Extract + Boswellia Serrata Extract + Olive Extract

Curcumin + Lacto GG

The combination of curcumin and Lactobacillus rhamnosus GG (LGG) might help decrease brain inflammation by acting on the gut-brain axis and exhibiting direct anti-inflammatory properties, as indicated by research that merges curcumin with LGG or other probiotics.

Curcumin alleviates neuroinflammation by inhibiting inflammatory pathways such as NF-κB and encouraging M2 microglia polarization. Meanwhile, LGG promotes gut health, which can beneficially affect the brain's inflammatory condition via the gut-brain axis.
 
Curcumin + Lacto GG + Lecithin
A blend of curcumin, Lactobacillus rhamnosus GG (LGG), and lecithin could provide advantages in lowering brain inflammation by promoting gut health and increasing the bioavailability of curcumin.

The probiotic LGG functions by enhancing the gut microbiome's health, which has a strong connection to the brain via the gut-brain axis.

It aids in restoring the gut barrier function, stopping inflammatory substances from entering the bloodstream and affecting the brain.

Lacto GG Probiotic

Lacto GG Probiotic is crafted with Lactobacillus rhamnosus GG, a well-known and widely studied probiotic strain. This unique supplement is designed to help maintain a healthy gut, support digestion, and promote overall wellness for the whole family.
LACTOGG® is produced in Hong Kong or the US,  with ingredients obtained from Europe, although the exact formulations and distribution differ by region, featuring various versions for markets such as Singapore and Malaysia.
The primary probiotic strain, Lactobacillus rhamnosus GG (LGG), was first identified in the United States by researchers in Boston.


VitaHealth  Supa  Garlic Plus + Kordel's Flamgo + Kordel Bio-Curmin, +  Lacto GG +  HMS Concept CoQ10 Plus.
This combination is the Most Potent for reducing Brain Inflammation:
Omega-3 fatty acids, particularly EPA and DHA present in fish oil, are vital for proper brain function and exhibit strong anti-inflammatory properties.
CoQ10 serves as an antioxidant that is crucial for mitochondrial energy production and offers protection against brain inflammation.
Lacto GG is a thoroughly studied probiotic that can affect the gut-brain axis to mitigate inflammation.
Curcumin, the active component of turmeric, is a potent anti-inflammatory agent capable of traversing the blood-brain barrier.

Quercetin:

Studies suggest that quercetin has the potential to diminish brain inflammation by inhibiting crucial inflammatory pathways such as NF-κB and the NLRP3 inflammasome. This action leads to a decrease in inflammatory cytokines and promotes the activation of advantageous antioxidant and cellular energy pathways, including Nrf2 and AMPK.


Life Extension, Optimized Quercetin
Life Factor Quercetin Plus CoQ10
Natural Factors Quercetin

Black Garlic Extract

Black garlic extract appears to be effective in lowering brain inflammation thanks to its anti-inflammatory characteristics. These benefits are linked to compounds such as S-Allylcysteine (SAC) and others that help reduce pro-inflammatory cytokines and alleviate oxidative stress.

Horbäach Aged Black Garlic
Life Extension, Aged Black Garlic
Vitamatic, Fermented Black Garlic
Naturewells Black Garlic Extract
KORDELS AGE BLACK GARLIC
Allisaq Capsule (500mg) Aged (Black) Garlic Extract

Olive Leaf Extract


Research indicates that Olive Leaf Extract (OLE) may aid in diminishing brain inflammation owing to its polyphenolic compounds, which possess antioxidant and anti-inflammatory characteristics that safeguard brain cells.

OLE functions by lowering oxidative stress and inhibiting pro-inflammatory molecules, demonstrating promise in offering protection against neurodegenerative disorders such as Alzheimer's and Parkinson's disease.

Olive Leaf Extract:

Carlyle Olive Leaf Extract

NOW Foods, Olive Leaf Extract
Healthy Care Olive Leaf Extract
Swanson, Olive Leaf Extract
Health Builder OLIVE LEAF EXTRACT
California Gold Nutrition, EuroHerbs™  Olive Leaf Extract
Nutricost, Olive Leaf Extract
Nature's Way, Premium Extract, Olive Leaf
DE VENUS BLACK SEED OIL+SACHA INCHI OIL+OLIVE LEAF EXTRACT

HEALTH BENEFITS of Olive Leaf Extract::
- Strengthens the body's immune system.
- Prevents viral diseases such as HIV, herpes and influenza
- Reduces sore throats, chronic sinusitis, skin diseases and pneumonia
- Eliminates symptoms of various types of infections including yeast, fungus, bacteria, viruses,   various protozoa parasites
- Effective in treating chronic fatigue syndrome, watery feet, arthritis, psoriasis
- Lowers blood pressure
 
Black Seed Oil + Olive Leaf Extract:
The combination of black seed oil with olive leaf extract can be more effective, as they might show a synergistic effect, boosting their joint antioxidant and anti-inflammatory benefits for improved health. This blend supports the immune system, heart health, skin health, and digestive health, making it a potentially strong natural supplement.


Brazilian Green Propolis

Research indicates that green propolis possesses anti-inflammatory and neuroprotective properties that may aid in decreasing brain inflammation, especially Brazilian green propolis. Its anti-inflammatory effects mainly function by preventing the activation of inflammatory cells in the brain, including microglia and astrocytes.
 
Brazilian Green Propolis contains more than 300 compounds and majority of them are forms of polyphenols. Polyphenols are packed with antioxidants which protect the body’s tissues against oxidative stress and associated pathologies such as cancers, coronary heart disease and inflammation.

Research shows that propolis has the ability to block or lessen the production of several pro-inflammatory cytokines, which are signaling proteins that contribute to inflammation. Notable examples are tumor necrosis factor-alpha (TNF-\(\alpha \)) and interleukins (IL-1\(\beta \), IL-6), both of which are crucial in the process of neuroinflammation.

The two major components which are Artepillin C and flavonoids helps to strengthen immunity and improve recovery.

Krill Oil


Krill oil might assist in lowering brain inflammation due to its content of anti-inflammatory omega-3 fatty acids (DHA and EPA) and the antioxidant astaxanthin. These elements work together to shield against neuroinflammation and promote cognitive health.
Research, including studies on animals, indicates that the components of krill oil can reduce oxidative stress, block neuroinflammatory factors, and preserve the blood-brain barrier, which may help protect against neurodegenerative diseases such as Alzheimer's.

Vitamode Krill Oil 1000mg
Duoleaf Krill Oil Plus
Labo Nutrition Perfect Krill EX Antarctic Krill Omega 3 Oil
HEALTHY CARE Wild Krill Oil
Swisse Deep Sea Krill Oil 1000mg

Astaxanthin

Astaxanthin has the ability to lessen brain inflammation by functioning as a strong antioxidant and anti-inflammatory substance that penetrates the blood-brain barrier. It has been demonstrated to block neuroinflammatory pathways, lower oxidative stress, and stop the activation of microglia, thereby safeguarding brain cells from harm.
Naturewells Astaxanthin Carotenoid

Astaxanthin: The Most Powerful Antioxidant


✅ 6,000 times stronger than vitamin C
✅ 1,000 times stronger than CoQ10
✅ 550 times stronger than Vitamin E (a-tocopherol)
✅ 550 times stronger than Green Tea
✅ 75 times stronger alpha-lipoic acid
✅ 40 times stronger than beta-carotene
✅ 17 times more potent than grape seed extracts
✅ Suppresses DNA damage

Other Health Benefits Of Astaxanthin

✅ Anti-inflammatory And Pain Relief
✅ It Promotes Skin Health
✅ Endurance And Fatigue
✅ Promotes Eye Health
✅ Cardiovascular Health And Blood Pressure
✅ Astaxanthin Promotes A Healthy Brain
✅ Astaxanthin And Male Fertility
✅ Diabetes And Obesity
✅ Immune System Boost

Naturewells Astaxanthin Carotenoid
NOW Foods Astaxanthin
Life Extension Astaxanthin with Phospholipids

Coenzyme Q10 (CoQ10)


Coenzyme Q10 (CoQ10) has the ability to diminish brain inflammation,with research indicating that it possesses antioxidant and anti-inflammatory characteristics that aid in safeguarding against neuroinflammation and associated harm in situations such as stroke and traumatic brain injury (TBI). CoQ10 operates by lowering pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α, while also enhancing mitochondrial function, which is essential for maintaining overall brain health and alleviating the cellular stress that drives inflammation.


HMS Concept CoQ10 Plus
Ingredients:
Coenzyme Q10 (Ubidecarenone)   150mg
L-Carnitine Fumarate                     125mg
Pine Bark Extract                              5mg
Alpha Lipoic Acid                          100mg
Vitamin D3                                    200 IU
Vitamin E                                        25 IU

Vitamode® CoQ10 Ubiquinol 100mg
NOW Coenzyme Q10 Nutritional Capsules
VitaHealth CoQ10 100mg Plus

MEGALIVE CoQ10 150mg Plus
Ingredients:
Coenzyme Q10 (Ubidecarenone) 150mg, L-Carnitine Fumarate 100mg, Alpha Lipoic Acid 20mg, Pine Bark Extract (Pinus Pinaster) 30mg.

Nutriva Oliferin CoQ10 200mg Plus Softgel 90's
Each softgel contains:
- Coenzyme Q10 (Ubidecarenone) ---- 200mg
- Vitamin K2 ---- 30mcg
- Vitamin D3 ---- 300 IU
- Vitamin E ---- 7.5 IU

L-carnitine and CoQ10

L-carnitine has the ability to decrease brain inflammation via several mechanisms, such as its antioxidant properties, enhancing mitochondrial function, and managing inflammatory markers like TNF-α and IL-6.
Research shows that it offers neuroprotective benefits in situations like traumatic brain injury, cerebral ischemia, and neurodegenerative disorders.

Studies suggest that the combination of L-carnitine and CoQ10 could aid in lowering brain inflammation due to their synergistic properties. It is thought that they function by mitigating oxidative stress, which is a major factor in neuroinflammation, and can be utilized together to tackle issues such as migraines and various neurological disorders.

By combating oxidative stress and inflammation, this pairing has demonstrated promise in lessening glial responses in the brain and reducing inflammation markers.

Red Yeast Rice:

Research suggests that red yeast rice may have a beneficial effect on brain inflammation through its antioxidant and anti-inflammatory properties.
It contains compounds with both antioxidant and anti-inflammatory effects that may counteract inflammation in the brain
.

Polyphenols present in olive fruit extract have demonstrated potential in alleviating brain inflammation.These neuroprotective benefits are ascribed to their potent anti-inflammatory and antioxidant characteristics.

Powerlife Arrespid

Ingredient:
Monascus Purpureus (Red Yeast Rice) 490mg, Olea Europaea (Olive Fruit) 50mg
Contains of Red Yeast Rice + Olive Fruit
i) Red yeast rice (standardized extract*) 490mg contains 4900 mcg of Monacolin K that can lower Total Cholesterol and LDL naturally
ii) Olive fruit extract** 20mg contains more than 5mg of Hydroxytyrosol that can protect heart vessel


Supplements that can be taken alongside red yeast rice (RYR) consist of CoQ10, Omega-3 fatty acids, olive fruit extract, berberine, nattokinase, and phytosterols. These can improve cholesterol-lowering effects, reduce inflammation or offer extra cardiovascular advantages.

Some RYR products on the market also contain vitamins, plant extracts such as green tea extract, or probiotics.

Magnesium


Magnesium has the potential to alleviate brain inflammation by blocking inflammatory pathways, especially the activation of NF-κB, which results in the generation of pro-inflammatory cytokines.


A deficiency in magnesium is linked to increased levels of brain inflammation, and ensuring sufficient magnesium levels can aid in the regulation of inflammatory responses, maintain neuronal integrity, and lower the risk of neurodegenerative disorders.

Magnesium L-Threonate, Magnesium Glycinate,  Magnesium Acetyl Taurate, and  Magnesium gluconate are types of magnesium that can effectively cross the blood-brain barrier, helping to lower neuroinflammation. Among these, Magnesium L-Threonate stands out as a powerful option because it directly boosts magnesium levels in the brain and helps regulate calcium, thereby decreasing inflammation.

[Life Extension] Neuro-Mag, Magnesium L-Threonate
VITAMODE MAGNESIUM L-THREONATE
Now Foods Magtein Magnesium L-Threonate
KAL, Think Magnesium L-Threonate with Magtein
Powerlife Magnesium Bisglycinate
NHF Magnesium Glycinate
Solaray Magnesium Glycinate
LAC Magnesium gluconate & magnesium oxide
Magtein  Magnesium L-Threonate

Note: Taking magnesium by itself can assist with particular health issues, like improving sleep or reducing anxiety (glycinate), easing muscle cramps (glycinate, malate), or serving as a laxative for constipation (citrate, oxide).
 
Certain supplements and medications, including high amounts of zinc, calcium, or certain antibiotics, may hinder magnesium absorption. Consuming magnesium separately can help avoid these interactions.

Vitamin D should be taken with magnesium. Because magnesium is necessary for the body to convert vitamin D into a form that can be used, the two minerals function in concert. Combining them can increase vitamin D's benefits and stop a deficit from getting worse.

MSM (methylsulfonylmethane)

MSM has the potential to diminish brain inflammation by suppressing inflammatory markers, enhancing antioxidant levels, and safeguarding against oxidative stress, which may provide a protective benefit against specific forms of brain injury and neurodegenerative diseases.

Powerlife UC MSM
Every sachet of Powerlife UC MSM Plus contains:
✨Methylsulfonylmethane 3000 mg
✨Chicken cartilage extract 40 mg
(Providing 10 mg total collagen)
✨Ascorbic acid (Vitamin C) 100 mg

Live-well OsteMSM
• MSM (Methylsulfonylmethane) is a natural form of sulphur found in our living tissues
• Delivers sulphur to the body in a useable way to help maintain the structure of connective tissues
• MSM widely used together in combination with Glucosamine & Chondroitin for relief of joint pains.

Vitahealth Flexiplex HA + MSM
- Contains 60mg hyaluronic acid for improved joint lubrication
- With 500mg MSM to support cartilage resilience and ease joint pain

Dandelion, Milk Thistle, Phyllantus Niruri


Research indicates that dandelion could aid in diminishing inflammation, which may encompass brain inflammation,
owing to its abundant supply of antioxidants and anti-inflammatory substances such as polyphenols and sesquiterpene lactones.
Studies indicate that specific compounds found in dandelion, including flavonoids and taraxasterol, possess anti-inflammatory and antioxidant characteristics that may aid in safeguarding against neuroinflammation,which refers to inflammation within the brain.

Studies indicate that milk thistle extract could aid in diminishing brain inflammation,
primarily attributed to its active ingredient, silymarin. Silymarin is known for its potent anti-inflammatory and antioxidant characteristics, which are thought to provide a neuroprotective benefit.

Some research indicates that Phyllanthus niruri extract could help decrease brain inflammation, highlighting its potential to safeguard against neurological damage caused by stress and neurodegenerative diseases.

PowerLife Hepapho
Each vegecap contains:
• Milk Thistle Extract (Semen Silybum Marianum) 200mg
• Phyllantus Niruri Extract (Herba Phyllantus Niruri) 150mg
• Dandelion Extract (Radix Taraxacum Officinale) 80mg

BlackPepper Extract (BioPerine)


Research suggests that piperine, the active ingredient in BioPerine, exhibits anti-inflammatory and neuroprotective characteristics that could aid in diminishing brain inflammation.
Piperine has demonstrated significant antioxidant and anti-inflammatory effects, which are essential for addressing neuroinflammation.

Mixing ginger extract with flaxseed oil and BioPerine could enhance the overall effectiveness and absorption of the beneficial properties found in these ingredients.

BioPerine is recognized for its ability to greatly boost the absorption of other nutrients by enhancing bioavailability, while flaxseed contributes anti-inflammatory and antioxidant properties, and ginger provides comparable health advantages.

Product:
Source Naturals BioPerine
Nutricost Bioperine (Black Pepper Extract) 10mg
Piping Rock BioPerine Black Pepper Extract, 10 mg
Herlia® Naturals Ginger Vita Extract Tablets
HERBABUMI HALIA MADU BENTONG SOFTGEL
Horbaach Ginger Root Capsules
21st Century Flaxseed oil

Piperine also enhances the absorption of various compounds such as curcumin, beta-carotene, selenium, Co-enzyme Q10, resveratrol, and various other vitamins and minerals, making them more bioavailabe for the body to use.

Astaxanthin

Astaxanthin has demonstrated the ability to diminish brain inflammation by functioning as a powerful antioxidant and anti-inflammatory substance. It crosses the blood-brain barrier and influences microglial polarization as well as inflammatory signaling pathways. Additionally, it offers protection against oxidative stress and may help mitigate cognitive deficits linked to neuroinflammation in a range of neurological disorders.

VITAMODE Astaxanthin Plus Glutathione Capsule
Bio-life Astaxanthin 6MG

Swisse Ultiboost Astaxanthin Glutathione Plus
Swisse Ultiboost Astaxanthin - Glutathione Plus is formulated with astaxanthin, glutathione, nicotinamide, vitamin c and vitamin e to nourish the body and maintain overall well-being.

Mushroom Extract:

Mushroom extracts have demonstrated potential in alleviating brain inflammation, including: Reishi, Cordyceps, Tiger Milk Mushroom, Turkey Tail, Maitake, Lion’s Mane, Shiitake, Chaga, Oyster, Enokitake, and Wood Ear mushrooms.


Reishi mushrooms (Ganoderma lucidum) demonstrate potential in alleviating brain inflammation, commonly known as neuroinflammation. Studies, mainly conducted on cells and animals, suggest that its anti-inflammatory and antioxidant characteristics may positively impact brain health.

Inhibition of inflammatory markers: A specific study found that a lipid-rich fraction obtained from the sclerotium of the Tiger milk mushroom reduced the production of inflammatory markers including nitric oxide (NO), iNOS, and COX2 in cultured BV2 microglial cells, which function as immune cells in the brain.

The turkey tail mushroom has the potential to alleviate brain inflammation owing to its anti-inflammatory characteristics, antioxidants, and immune-modulating substances such as polysaccharides and beta-glucans, which safeguard cells against oxidative stress and promote the health of the nervous system.

Some studies suggest that Cordyceps, especially its component cordycepin, may alleviate brain inflammation by suppressing pro-inflammatory immune cells and enhancing anti-inflammatory responses.

NHF Trimuno
Extract from various types of mushrooms, only selecting sporocarps to obtain the highest concentration of triterpenoids and polysaccharides
Ingredients:
Sclerotium Hericium Erinaceus 400mg / Sclerotium Lignosus Rhinocerus 400mg / Sclerotium Reishi (Ganoderma Lucidum)Extract 400mg / Sclerotium Phellinus Linteus Extract 400mg / Sclerotium Maitake(Grifola Frondosa) Extract 400mg / Sclerotium Inonotus Obliquus (Mushroom)Extract 400mg / Fructus Amomum Villosum Lour Extract 400mg / Sclerotium Coriolus Versicolor Extract 400mg / Sclerotium Cordyceps Sinensis Extract 400mg / Sclerotium Agaricus Blazei Murill Mushroom Extract 400mg.

ElfaHex 

ELFAHEX contains a patented ingredient, Mycelium Immuno Modulator Extract, or also known as MIME, that is extracted from mushrooms that have been researched to possess a high potency of polysaccharides in the form of ACETYLATED alpha-glucan. The patented cultivation process of ELFAHEX ensures that the identity of the MIME cells remains the same for our body’s easy absorption.

Vitamin k2 + Vitamin D3


Research indicates that vitamin K2 may help decrease brain inflammation, as evidenced by studies demonstrating its capacity to block pro-inflammatory markers, safeguard against oxidative stress, and enhance neurological functions.
Vitamin K2 serves as a powerful neuroprotective agent, traversing the blood-brain barrier and influencing inflammatory pathways such as NF-κB to promote brain health and cognitive abilities.

Vitamin D3 has the ability to decrease brain inflammation by influencing the immune system and lowering the production of pro-inflammatory cytokines.
Research indicates that vitamin D possesses immunomodulatory properties, offers protection against oxidative stress and neuronal injury, and boosts the presence of anti-inflammatory microglia in the brain.

Products:
Vitahealth Vitamins K2 + D3
Horbaach Vitamin D3 5000IU + K2 MK-7 100mcg
Now Foods, Vitamin D3 + K2
Solaray, Vitamin D3 + K2
Powerlife K2D3 (Vitamin D3 1000 IU, Vitamin K2 120 mcg
Doctor's Best, Natural Vitamin K2 MK-7 with MenaQ7

Spirulina

Spirulina helps decrease brain inflammation thanks to its strong antioxidant and anti-inflammatory qualities, especially from its active ingredient, phycocyanin.

Research indicates that it can lower neuroinflammation markers, diminish oxidative stress, safeguard against neuronal damage, and enhance brain health..

Elken Spirulina
Atomy Spirulina
PipingRock Spirulina
Biocare Spirulina
NHF Organic Spirulina
Swisse High Strength Organic Spirulina
Cosway Certified Organic Spirulina
Belixz Spirulina

AFA Extract ( Aphanizomenon Flos-Aquae)


Products:
HA SMART HA'AFA (Aphanizomenon Flos-Aquae)
Enerflex AFA 15
AFX MEDI AFA
Cellmaxx Plus (AFA-based)
Stemtech AFA Extract Plus
BMS Organics Tri-Algae (300 Tablets) 200mg
Duoleaf SCN-Hanz 30's x 2
DM Aesthetics Stem Cell Enhancer
BeYoung (AFA Aphanizomenon flos-aquae) 野生蓝绿藻

AFA Extract, or Aphanizomenon Flos-Aquae, is a super blue green algae known for its exceptional nutritional composition.
Supports the body’s natural renewal system by supporting the release of more healthy adult stem cells into the bloodstream that helps the body maintain and repair tissue and organs.

Aphanizomenon flos-aquae (AFA), particularly its extract, has demonstrated promise in alleviating brain inflammation by addressing oxidative stress and regulating glial cell function. The anti-inflammatory properties are linked to its abundant presence of phycocyanins, carotenoids, and various other antioxidant substances that suppress inflammation and safeguard against neurodegeneration.

Probiotic


Probiotic strains
that have anti-inflammatory properties include
Lactobacillus Rhamnosus, Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium breve, and various Lactobacillus species. These strains may help reduce brain inflammation by influencing the gut-brain axis, enhancing gut barrier function, and lowering inflammatory markers.

Lactobacillus plantarum: Research using animal models of neurodegenerative diseases indicates that this strain can lessen neuroinflammation by reducing microglia activation (the brain's immune cells) and blocking the production of pro-inflammatory cytokines.

Bifidobacterium breve: This strain has shown anti-inflammatory benefits in the brain and has been linked to improved cognitive function in animal studies related to Alzheimer's disease. A human study also indicated significant cognitive improvements in older adults with mild cognitive impairment.

Clostridium butyricum: This strain has been found to offer protection against cerebral ischemic injury (stroke) by reducing inflammation, decreasing cell death (apoptosis), and boosting antioxidant enzyme activity.

Lactobacillus rhamnosus GG (LGG) has shown promise in lowering brain inflammation via the gut-brain axis. Studies indicate that it aids in repairing the gut-brain barrier, decreases pro-inflammatory cytokines like IL-6, IL-1β, and TNF-α, and boosts anti-inflammatory cytokines such as interleukin-10 (IL-10). Additionally, LGG's role in adjusting the gut microbiota and reinforcing the blood-brain barrier helps enhance cognitive functions impacted by inflammation.


Recommended Products:


Lacto GG Probiotic 20 Billion CFU

NGREDIENTS. Inulin, Lactobacillus Rhamnosus Gg (Atcc 53103), Vegetable Capsule, Magnesium Stearate, Silicon Dioxide.

PHM OHMS PROBIOTICS GOLD
Each capsule contains:
•Lactobacillus Acidophilus La-14 - 185mg
•Bifidobacterium Infantis M-63 - 25mg
•Lactobacillus Plantarum NBRC 15891 - 5mg
•Lactobacillus Brevis NBRC 3345 - 2mg
•Streptococcus Thermophillus NBRC 13957 - 245mg
•Lactobacillus Casei NBRC 15883 - 5mg
•Bifidobacterium Longum BB536 - 135mg
•Lactobacillus Bulgarcius NBRC 13953 - 2mg

GKB G-PRO GOLD 500MG
10 strain probiotics: 80 billion CFU per capsule
Bifidobacterium breve
Bifidobacterium bifidum
Lactobacillus brevis
Lactobacillus plantarum
Lactobacillus bulgaricus
Lactobacillus reuteri
Lactobacillus casei
Lactobacillus acidophillus
Lactobacillus rhamnosus
Lactobacillus paracasei

Atomy Probiotics Plus
Ingredients:
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus casei
Lactobacillus acidophilus
Lactobacillus paracasei
Lactobacillus fermentum
Lactobacillus helveticus (also includes the Rosell-52 strain)
Lactobacillus plantarum (from kimchi)
Bifidobacterium longum (also includes the Rosell-175 strain)
Bifidobacterium breve
Bifidobacterium bifidum
Bifidobacterium lactis
Streptococcus thermophilus

Tart Cherry Extract:

Tart cherries demonstrate potential in alleviating brain inflammation owing to their abundant anthocyanin and polyphenol content, which exhibit antioxidant and anti-inflammatory characteristics. These compounds can safeguard microglia, the immune cells located in the brain, from excessive activation by inflammatory stimuli. The intake of tart cherries may reduce inflammatory markers, shield brain cells from oxidative stress, and enhance cognitive abilities such as working memory and attention.


NusaPure Tart Cherry

Lindberg Tart Cherry with Turmeric
Gemedy Bromelain with Tart Cherry & Turmeric
Swanson Tart Cherry Turmeric & Boswellia
NOW Foods Tart Cherry, 500 mg
[Life Extension] Tart Cherry with CherryPURE®
Piping Rock Ultra Tart Cherry
Carlyle Tart Cherry Extract
Nutricost Tart Cherry
Piping Rock Tart Cherry and Turmeric Complex

Sulforaphane


Sulforaphane has the ability to diminish brain inflammation
by traversing the blood-brain barrier, stimulating antioxidant pathways (such as Nrf2-HO-1), and adjusting inflammatory responses in microglia.
Within the brain, microglia function as immune cells. Sulforaphane aids in the regulation of these cells by encouraging their transition from a pro-inflammatory state to an anti-inflammatory state. This process mitigates microglial-mediated neuronal damage and decreases inflammation.

Piping Rock Sulforaphane
Swanson  Sulforaphane
LAC Vegishield

Moringa Leaf Extract:

Moringa Oleifera Leaf Extract demonstrates promise in alleviating brain inflammation due to its anti-inflammatory and antioxidant characteristics, as evidenced by numerous studies focused on neurodegenerative disorders and stroke models. This extract has the ability to lower pro-inflammatory cytokines, block inflammatory signaling pathways such as NF-κB, and reduce indicators of oxidative stress, all of which play a role in its neuroprotective benefits.

 Products:

Naturewells Moringa Oleifera Leaf Extract

Biocare Moringa
Bioleaf MORINGA Oleifera
Rosabella Moringa Capsules
Nano Singapore Moringa Leaf 1100mg
Devida Moringa Oleifera Extract
Carlyle Moringa Oleifera 6000 mg
Nature's Truth Moringa Oleifera 6000mg

Arabic gum

Arabic gum seems to offer potential advantages in alleviating brain inflammation by lowering inflammatory markers and enhancing antioxidant activity.

It functions as a prebiotic, thereby improving the gut-brain axis, and may also provide protective effects against neurotoxicity and oxidative stress, conditions that frequently occur alongside inflammation.


Natural & Organic Arabic Gum AL-IMAM
Habbatusyifa Arabic gum Capsule
Basharul Amia Arabic Gum

T&I Sacha Inchi Oil Capsule 600mg
Ingredients: Sacha Inchi Extra Virgin Oil (70%), Sea Buckthorn Oil (10%), Grape Seed Oil (10%), Eucommia Seed Oil (10%)

 Sacha Inchi Extra Virgin Oil (70%)
• #LowersCholesterol, regulates blood lipids, and protects #HeartHealth.
• Powerful #Antioxidant properties slow aging and repair cells.
• Moisturizes and nourishes #SkinAndHair.
Sacha Inchi Extra Virgin Oil has the potential to alleviate brain inflammation owing to its rich Omega-3 fatty acid content and antioxidant characteristics. These elements can suppress inflammation, safeguard cells from free radical damage, and enhance neurological well-being. Consistent intake of Sacha Inchi oil, when paired with a nutritious diet and physical activity, may assist in preventing chronic inflammation and fostering optimal brain function.

Sea Buckthorn Oil (10%)
• Rich in Vitamin C, promotes #CellRepair and #SkinHealth.
• Enhances #Immunity, keeping you resilient against external threats.
Sea buckthorn oil demonstrates potential in alleviating brain inflammation,
with research suggesting its antioxidant, anti-inflammatory, and neuroprotective characteristics. The abundance of omega fatty acids, flavonoids, and carotenoids plays a significant role in this effect by blocking inflammatory pathways and diminishing oxidative stress in brain tissue.

Grape Seed Oil (10%)
• Strong #Antioxidant, reduces #Inflammation, and neutralizes free radicals.
• Regulates #BloodSugar, promoting balance in the body.
Research regarding grape seed oil and its extract indicates that it may alleviate brain inflammation owing to its antioxidant and anti-inflammatory characteristics. The compounds found in grape seed, including proanthocyanidins, have the ability to neutralize free radicals, inhibit inflammatory responses, and offer protection against neurodegenerative disorders such as Alzheimer's disease by diminishing brain inflammation and Aβ accumulation.

Eucommia seed oil:
• Relieves #JointPain and strengthens #BoneHealth.
• Boosts the #ImmuneSystem for better overall health.
Extracts have demonstrated a reduction in the levels of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6, in both blood and brain tissue.
Research suggests that Eucommia ulmoides is capable of mitigating neuroinflammation by blocking essential inflammatory pathways, such as TLR4/p38 MAPK and NF-κB.

Chinese Hawthorn (山楂, shān zhā)

Hawthorn may offer advantages for cardiovascular health owing to its antioxidant and anti-inflammatory characteristics, which encompass impacts on blood pressure and cholesterol levels, and it might also assist with anxiety, digestive health, and the regulation of blood sugar.

Hawthorn has shown anti-inflammatory and neuroprotective properties, which include the reduction of brain inflammation and cellular damage, indicating possible benefits for disorders related to brain inflammation, such as strokes and neurodegenerative conditions. Its bioactive constituents, which include polyphenols like flavonoids and proanthocyanidins, play a role in these effects by modulating the immune response and functioning as antioxidants.

Hawthorn Tea:
Ingredients:
Dried hawthorn slices - 20 slices
Water (2000 ml)
Honey to taste

Method:
Wash the berries and place them in a saucepan.
Pour the water over the berries and bring to the boil.
Simmer for about 15 minutes
While still warm, sweeten with honey if you like.
Allow to soak the boiled hawthorn in the water until cool
You can keep the strained and cooled tea in the fridge .

Honey demonstrates promise in mitigating neuroinflammation owing to its anti-inflammatory and antioxidant properties, such as flavonoids and polyphenols, which counteract oxidative stress and lower pro-inflammatory agents in the brain.

Note: If you have knee pain, you can drink this hawthorn tea for a week. Drink one cup per day is recommended.
Andrographolide 穿心莲 (Chuān Xīn Lián)
Indication: Traditionally used for relief of flu,  fever, cough, cold and sore throat.

Andrographolide (Green chiretta)  has demonstrated the ability to suppress the activation of microglia, the primary immune cells in the brain, which can become excessively active and lead to inflammation.


Available in capsules:

Nova Ezmune Andrographolide + Grape Seed Extract.
Strengthen Immune System Anti inflammatory Anti Oxidant
Reduce inflammation and antioxidant, empower body defense.
- Enhance the phagocytic and clearance ability of macrophages, assist in the rapid removal of pathogens in abdominal cavity infection, and enhance intestinal immune response.
- Grape Seed Proanthocyanidins
- Contains flavonoid antioxidants Proanthocyanidins (OPCs), which have antioxidant, anti-inflammatory, wound healing, and cardiovascular protection effects.

Androprotec 100mg Tablet
Each 680mg tablet contains Folium Andrographis Paniculate Extract 100mg (Containing 50mg Andrographolide)

Note: You can soak 3 fresh leaves in  ½ cup of hot water. Add a teaspoon of honey.

Bergamot


Bergamot may assist in diminishing brain inflammation,
as its extracts have demonstrated neuroprotective and anti-inflammatory characteristics in animal studies by lowering inflammatory markers such as IL-1β, IL-6, and TNF-α.

The anti-inflammatory properties are ascribed to the abundant flavonoid content found in bergamot, which encompasses compounds such as hesperidin and naringin. These compounds seem to function by modulating essential pathways associated with inflammation and suppressing the synthesis of inflammatory cytokines.


Bergamot provides advantages for cardiovascular health by aiding in the reduction of cholesterol and triglycerides, enhances metabolic health through better insulin sensitivity, and promotes mental well-being by alleviating anxiety and enhancing mood. Additionally, it contributes to digestive health, supports skin health with its antiseptic qualities, and functions as an antioxidant and anti-inflammatory agent owing to its rich flavonoid and polyphenol content.


nutricost Citrus Bergamot
Solaray Vital Extracts Bergamot
Nn Berga3H Bergamot Fruit Extract
Schwartz Ultra Concentrated Citrus Bergamot

Boswellia

Boswellia may help alleviate brain inflammation, especially cerebral edema (swelling of the brain) in individuals receiving radiotherapy for brain tumors. The anti-inflammatory effects are linked to its active components, known as boswellic acids, which are believed to obstruct pro-inflammatory pathways and may possess antioxidant and neuroprotective properties. Boswellic acids are recognized for their ability to inhibit 5-lipoxygenase (5-LO), an enzyme responsible for producing leukotrienes, which contribute to inflammation. One of the most promising research areas is the potential of boswellia to diminish cerebral edema (brain swelling).


Swanson Full Spectrum Boswellia
NOW Foods Boswellia Extract
Opceden Bromelain Boswellia Curcuma
Carlyle Boswellia Extract Capsules 1,200mg
PipingRock Standardized Boswellia Complex 800mg
Himalaya Boswellia
Solaray MSM with Turmeric, Boswellia & Devil's Claw
Oliferin Joint Flex Triva -Boswellia Serrata Extract+ Olive Extract+ Curcumin Extract.

Sea buckthorn Oil

Research indicates that flavonoids found in sea buckthorn, including isorhamnetin, are capable of crossing the blood-brain barrier and alleviating inflammation. These flavonoids work by blocking inflammatory pathways such as NF-κB and MAPK, which are responsible for the release of pro-inflammatory agents.

D'Medy Sacha Inchi Oil + Sea Buckthorn Oil & Vitamin D3
Sea Buckthorn Oil with Omega-7
Borneo Fairy SACHA INCHI OIL+ SEA BUCKTHORN+TOCOTRIENOLS
Carlyle Sea Buckthorn Berry Oil Capsules
Bonlife Sea Buckthorn
ZEMVELO-2 - Sacha Inchi Oil + Vit E + Sea Buckthorn

Chlorella


Heavy metals
present in the body can lead to brain inflammation, a condition referred to as neuroinflammation. Metals such as arsenic, lead, mercury, and cadmium are harmful even in minimal quantities, whereas iron, copper, and zinc are vital nutrients but can become detrimental when present in excessive amounts.


These metals may enter the body via contaminated food, water, air, and various products, accumulating in tissues over time.


Heavy metals can trigger the activation of sentinel immune cells in the brain, including microglia and mast cells. This activation sets off a series of inflammatory responses and the release of proinflammatory cytokines, which contribute to neuroinflammation.


Chlorella is capable of removing a wide array of heavy and radioactive metals, such as mercury, lead, cadmium, arsenic, lead (Pb), zinc (Zn), cobalt (Co), copper (Cu), nickel (Ni), and uranium. It does this through a process called biosorption, where metal ions adhere to the surface and within the cells, and it can also bind to and eliminate radioactive isotopes like strontium (Sr) and technetium (Tc) from the body.

Other supplements like spirulina, cilantro, milk thistle, selenium, Vitamin C, alpha-lipoic acid, glutathione, probiotics, and Activated Charcoal can also assist your body in removing heavy metals.

Products:
Abeille D'Or Chlorella Gold

Abeille D'Or 益寶多 Chlorella Gold
PipingRock Organic Chlorella Spirulina 500mg
Japan Orihiro Chlorella
NOW Foods Certified Organic Chlorella, 500 mg
Biocare Chlorella Chewable Tablet
Cosway Yaeyama Chlorella
Eu Yan Sang Chlorella
Powerlife Multi Greens 410mg

Black Sesame Seed Extract

The extract of black sesame seeds comprises compounds that have demonstrated the ability to diminish brain inflammation in various studies conducted on animals and cells.
The anti-inflammatory properties are primarily ascribed to the lignans present in sesame seeds, especially sesamin and sesamol.
 
Products:

Blacsemenuro Vegetable Capsule


For More Information - Click here

Nature's Way Rosemary Leaf

Rosemary extract has the potential to decrease neuroinflammation, which refers to brain inflammation, thanks to its anti-inflammatory and antioxidant characteristics, mainly attributed to compounds such as carnosic acid and rosmarinic acid.
21st Century Flaxseed Oil 1000 mg

Flaxseed oil can help reduce inflammation, primarily due to its high concentration of the omega-3 fatty acid alpha-linolenic acid (ALA).
HERBS OF GOLD GRAPE SEED 500MG
Grape seed extract (GSE) demonstrates potential in alleviating brain inflammation owing to its potent antioxidant and anti-inflammatory characteristics, which counteract oxidative stress and promote proteostasis (protein homeostasis).
OMOGS DHA & PS
Effective Ingredient:DHA softgels contain 600mg of DHA and 100mg of Phosphatidylserine. DHA is an important part of the brain and retina, and the combination of both DHA+PS is needed for a stronger effect, helping to brain, eye and heart function.
Powerful health benefits:OMOGS DHA is specially formulated with Phosphatidylserine, which improves nerve cell function, regulates nerve impulse transmission, and enhances memory function.
Quality:Our DHA Omega-3 Essential Acid comes from Algae Oil (Marine Algae)

Highly Recommended Products To Reduce Inflammation

Infinity Phyto-Hr Complex

Each capsule (395mg) contains :
Green tea leaf extract             100mg
Wolfberry fruit extract            80mg
Grape seed extract                 50mg
White pine bark extract          40mg
Pomegranate fruit extract        25mg
Black pepper fruit                    20mg
Ginger root extract                   20mg
Black raspberry fruit extract     15mg
Blueberry fruit extract             15mg
Cranberry fruit extract             15mg
Strawberry fruit extract           15mg

Infinity Black Seed Oil Plus Olive Leaves Extract
Each softgel (950mg) contains:
Black Cumin Seed Oil     500mg
Olive Leaves Extract       150mg

Infinity Sacha Inchi Oil 1000mg with Vitamin D3 1000IU
Each softgel contains
Sacha Inchi Seed Oil          1,000mg
Vitamin D3                         1,000IU

Cat's Claw

Cat's claw can assist in diminishing brain inflammation, and several of the essential compounds have been recognized.
Studies indicate that these compounds are capable of traversing the blood-brain barrier and alleviating inflammation by suppressing pro-inflammatory elements.

Cat's claw is a herb that is well-regarded by the Indigenous peoples of Peru. It is utilized for the treatment of cancer, diabetes, ulcers, arthritis, and infections.
Nature's Answer, Cat's Claw
NOW Foods, Cat's Claw
Carlyle Cat's Claw Herb

Cat's claw is used as an analgesic and antiinflammatory agent to treat gastrointestinal, rheumatologic and other chronic inflammatory conditions.

Customers have reported that the Cat's Claw supplement is effective for alleviating pain, with one individual noting that it assists with chronic back pain.
Neuroprotective Herbs: Gotu Kola, Ginkgo biloba, Lion's Mane, Cat's claw, Saffron,
Turmeric, Triphala, Bacopa monnieri (Brahmi).

What are senescent cells?


Aging cells, known as senescent cells, can lead to brain inflammation as they build up over time and secrete pro-inflammatory substances, which are collectively referred to as the Senescence-Associated Secretory Phenotype (SASP). These substances can initiate a persistent inflammatory condition (neuroinflammation) in the brain, which plays a role in the decline associated with aging and neurodegenerative disorders such as Alzheimer's and Parkinson's by harming nearby cells and interfering with normal brain operations.

Supplements like  Piperlongumine (Long pepper), Curcumin, Fisetin, Resveratrol, Theaflavins (from black tea), EGCG (from green tea), Sulforaphane, Quercetin, Kaempferol (Black ginger), Sulforaphane, Lipoic acid, Gingerenone (Gingerenone A is a bioactive compound and polyphenol found in the rhizomes of ginger),  can clear away senescent cells.

Other supplements are also helpful to clear out senescent cells such as Black seed oil, Olive oil, Olive leaf extract, Spirulina, Chlorella, Grape seed extract and various berries ( Strawberry, Kiwi, Apple).

Fisetin is often viewed as being more effective than EGCG when it comes to eliminating senescent cells while EGCG mainly works to inhibit the detrimental functions of these cells, like diminishing the senescence-associated secretory phenotype (SASP). Fisetin, on the other hand, directly triggers apoptosis in senescent cells, resulting in their removal, while EGCG focuses mainly on the inflammatory signaling pathways that these senescent cells encourage.

Recommended Products:

Life Extension Bio-Fisetin

Fisetin supports healthy aging. But much of the fisetin you ingest turns to various metabolites through the digestive process. So we’ve created a formula that helps preserve fisetin for enhanced bioavailability.

CELLFEND Fermented Long Pepper Extract – Senolytic Agent – with Piperlongumine
Piperlongumine has been identified as a natural, plant-derived, potent senolytic, able to selectively kill senescent cells, protecting against age-related disorders.

Life Extention Theaflavin Standardized Extract
Black tea is packed with antioxidants. Those found in black teas, theaflavins & thearubigins, have researchers excited about their potential health benefits, including support for arterial health.

Life Extention Bio-Quercetin
Bio-Quercetin® uses a quercetin combined with fibers from fenugreek seeds to increase bioavailability.

Renue by Science  Fisetin (Liposomal)
Fisetin is a natural compound that supports healthy cells. LIPO Fisetin is designed to selectively target aging cells, fostering a clean and well-functioning internal environment.
Fisetin is a flavonoid that is a natural polyphenol and antioxidant.
It’s found in strawberries, apples, onions, and other plants that are particularly good at getting rid of senescent or “Zombie cells,” Fisetin has been called “The King of Senolytics”.
Senescent Cells:
One of the main reasons you age is due to cells no longer dividing as they get older.
These cells become useless and start to build up in your body triggering inflammation, gradually impairing your cellular function, and increasing your risk of age-related conditions.
Get Rid of “Zombie” Cells:
Scientists refer to these as Senescent cells, but are more commonly called “Zombie” cells. They are like little poison factories that do no useful work, but instead emit cytokines, which trigger inflammation in neighboring cells.

Infinity Phyto-Hr Complex
Each capsule (395mg) contains :
Green tea leaf extract              100mg
Wolfberry fruit extract             80mg
Grape seed extract                  50mg
White pine bark extract           40mg
Pomegranate fruit extract         25mg
Black pepper fruit                    20mg
Ginger root extract                   20mg
Black raspberry fruit extract    15mg
Blueberry fruit extract             15mg
Cranberry fruit extract             15mg
Strawberry fruit extract           15mg

Note: Omega-3 fish oil taken with EGCG has been shown to improve its obsorption and antioxidant activity. Vitamin C combined with bioflavonoids can work alongside EGCG, often enhancing their antioxidant activity and stability in a synergistic manner. Vitamin C has the ability to regenerate EGCG radicals back into their active form, which can elevate the overall antioxidant strength of the combination. Additionally, bioflavonoids are antioxidants in their own right and have demonstrated the ability to collaborate with vitamin C and EGCG to amplify protective effects against oxidative damage.


Carlyle Pomegranate Extract
Antioxidant Support: Pomegranates are rich in antioxidants, including punicalagins, anthocyanins, and ellagic acid, which help neutralize harmful free radicals in the body.
Pomegranate extract has the ability to decrease brain inflammation due to its polyphenol content, which offers both antioxidant and anti-inflammatory benefits. Research indicates that pomegranate extract can assist by blocking inflammatory pathways, minimizing oxidative stress, and decreasing inflammatory markers in the brain.

Naturmeric Black Turmeric 450mg

Anti-inflammatory powerhouse – supports joint health, reduces body pain & inflammation
Brain & memory support – boost focus, clarity & stress resilience
Immune defense – natural antioxidant protection

Black Turmeric (Curcuma caesia) extract has shown promise in alleviating brain inflammation thanks to its anti-inflammatory and antioxidant qualities, much like Curcuma longa (turmeric). It may function by inhibiting inflammatory cytokines and combating oxidative stress, thereby offering protection against neurodegeneration.

Studies on curcumin indicate that it can penetrate the blood-brain barrier and affect various inflammatory pathways within the central nervous system. It has demonstrated the ability to lower pro-inflammatory cytokines such as TNF-α and IL-1β, which play a role in neuroinflammation.
Carlyle Grapeseed Green Tea Pine Bark
Horbaach Pine Bark Extract


Pine bark extract might assist in lowering brain inflammation thanks to its antioxidant and anti-inflammatory characteristics. Studies indicate that it can reduce pro-inflammatory cytokines such as IL-1β and TNF-α, and research demonstrates that it can offer protection against neuroinflammation caused by issues like traumatic brain injury.
KSM-66 Ashwagandha might assist in lowering brain inflammation by combating oxidative stress and inflammation due to its antioxidant qualities. Research indicates that it can reduce inflammation markers and safeguard brain tissue from harm in models of conditions such as stroke and traumatic brain injury.
KSM-66 can suppress inflammatory markers like TNF-α, IL-1β, and IL-6 by downregulating pathways such as NF-κB, which are key drivers of neuroinflammation.
莲花清肺茶 Lian Hua Qing Fei Cha
𝗘𝗳𝗳𝗶𝗰𝗮𝗰𝘆: Clearing away heat and detoxification, Lungs tonic and nourishing, treat cough, sore-throat, fever, headache, cold and flu.
𝗜𝗻𝗴𝗿𝗲𝗱𝗶𝗲𝗻𝘁𝘀: Honeysuckle (金銀花), Herba Houttuyniae (魚腥草), Spica Prunellae (夏枯草), Herba Agastaches (藿香), Radix Isatidis (板藍根), Folium Isatidis (大青葉), Poria Cocos (茯苓), Apricot Kernels (杏仁), Radix Rhodiolae (紅景天), Rhizoma Phragmitis (蘆根), Herba Menthae (薄荷), white granulated sugar (白砂糖)

Honeysuckle is rich in bioactive compounds, including flavonoids and phenolic acids, which exhibit anti-inflammatory properties. Research in the scientific community indicates that honeysuckle extracts have the ability to lower pro-inflammatory cytokines, such as TNF-α and IL-6, while also inhibiting inflammatory pathways. This suggests that honeysuckle may serve as a potential therapeutic agent for a range of inflammatory conditions. All the herbs included in the ingredients possess anti-inflammatory properties that can effectively diminish brain inflammation.
AnHuiTang Honeysuckle Chrysanthemum Licorice Herbal Tea
🔆Ingredients: chrysanthemum,Licorice,Honeysuckle,Stevia leaf

Product Benefits/ Product Efficacy :
✔️ Clear heat and detoxify
✔️ Clear liver fire
✔️ Treats bad breath
✔️Promoting body fluid and quenching thirst
AnHuiTang Prunella Vulgaris & Comfrey Herbal Tea
Product Benefits/ Product Efficacy :
✔️ Clear heat and detoxify
✔️ Relieve Body Heat
✔️ Moisten Throat
✔️ Damp Heat
✔️ Improve Blood Circulation
王老吉 WANG LAO JI
Benefits: Clears heat, dampness, and dry mouth, and relieves sore throats and colds.

Hibiscus Tea

Hibiscus tea appears to be beneficial in lowering brain inflammation and safeguarding against neurodegenerative diseases such as Alzheimer's by blocking inflammatory markers and minimizing oxidative stress.

Hibiscus has demonstrated the ability to reduce the levels of pro-inflammatory cytokines like IL-1, IL-6, and TNF-α in brain cells.
Research indicates that hibiscus compounds can protect brain tissue from damage and inflammation by reducing pro-inflammatory cytokines and oxidative stress.

Organic Hibiscus Tea:
Boil one cup of water.
Add in a tea bag of the tea.
Steep for 10 minutes (Covered)
Serve as a tea on empty stomach.
Warning: Always purchase health supplements from Official Supplier. There are many fake (Counterfeit) products sold online.  It is crucial to seek advice from a healthcare professional prior to taking any supplements, especially if you have a metabolic disorder or taking any medication.
Disclaimer:-
The report here is for your understanding of the above health problems and not a substitute for professional medical care and should not be used treating a health problem or a disease and that the materials here are not meant as a substitute for professional medical prevention, diagnosis or treatment. Please consult with your physician, doctor, pharmacist, or health care provider before taking any home remedies or supplements or following any treatment suggested by anyone on this site. Only your health care provider, personal physician, or pharmacist can provide you with advice on what is safe and effective for your ailment.
Herbs can interact with other medicines. Do not take them together. Consult with your physician first. I do not claim that anything in my blog can cure certain diseases. That would be illegal. Instead, I believe that there isn’t, and never will be a one-stop ‘cure’ to all diseases, and that eliminating disease requires many changes including diet, exercise, and switching to healthy foods.
All trademarks, company names, product names ,and videos mentioned are the properties of their respective owners.
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